化学科学资料

Using the RA802 to monitor the uniformity of a drug product’s contents to ensure that the correct dose is delivered every time.

Application note: New methods for determining content uniformity of formulations

Using the RA802 to monitor the uniformity of a drug product’s contents to ensure that the correct dose is delivered every time.

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Many pharmaceutical materials are highly sensitive to changes in temperature and humidity which can affect their crystalline structure. Knowing the stability of these polymorphs and hydrates, in different conditions, is critical to ensure products are safe, efficient and can be patent protected.

Application note: Study the stability of pharmaceutical formulations with Raman microscopy

Many pharmaceutical materials are highly sensitive to changes in temperature and humidity which can affect their crystalline structure. Knowing the stability of these polymorphs and hydrates, in different conditions, is critical to ensure products are safe, efficient and can be patent protected.

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With so many components and properties, determining the composition, domain size and distribution of patent-expired commercially available formulations is highly desirable. This information creates opportunities to replicate an existing product without the need for lengthy development and prohibitive costs.

Application note: Investigate pharmaceutical solid dose products using the inVia confocal Raman microscope

With so many components and properties, determining the composition, domain size and distribution of patent-expired commercially available formulations is highly desirable. This information creates opportunities to replicate an existing product without the need for lengthy development and prohibitive costs.

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Whether at the research and development stage, or manufacturing, the inVia Raman microscope offers simple and fast transmission Raman analysis.

Application note: Transmission Raman for monitoring pharmaceuticals

Whether at the research and development stage, or manufacturing, the inVia Raman microscope offers simple and fast transmission Raman analysis.

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When formulating pharmaceuticals, it is important to understand the chemical composition and morphologies of the ingredients, as these can lead to changes in product performance. For example, active ingredient co-localisation and particle adhesion can affect the efficacy of formulation. This application note details how to use a Renishaw Raman system to conduct this type of analysis.

Application note: Combined chemical and particle distribution analysis of pharmaceutical powders

When formulating pharmaceuticals, it is important to understand the chemical composition and morphologies of the ingredients, as these can lead to changes in product performance. For example, active ingredient co-localisation and particle adhesion can affect the efficacy of formulation. This application note details how to use a Renishaw Raman system to conduct this type of analysis.

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This note looks at incidences of polymorphism in drug development including advantages and challenges.

Application note: Using Raman spectroscopy to tackle polymorphism, an industry problem

This note looks at incidences of polymorphism in drug development including advantages and challenges.

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An application note detailing the RA802's ability to deformulate the make-up of a transdermal nicotine patch.

Application note: Raman imaging for deformulating a transdermal patch

An application note detailing the RA802's ability to deformulate the make-up of a transdermal nicotine patch.

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Characterising the polymorphism of active pharmaceutical ingredients when developing a commercially viable product.

Application note: Rapid polymorph identification with the RA802 Pharmaceutical Analyser

Characterising the polymorphism of active pharmaceutical ingredients when developing a commercially viable product.

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This document focuses on concentration measurements but the principles detailed are also applicable to other quantitative measurements, such as stress/strain.

Technical note: Quantitative Raman spectroscopy

This document focuses on concentration measurements but the principles detailed are also applicable to other quantitative measurements, such as stress/strain.

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This technology note illustrates the benefits of combining dedicated analysis software with a high-performance Raman instrument and how Renishaw supplies an effective, user-friendly solution to provide complementary information to the multitude of established HTS techniques commercially available.

Technical note: Polymorph identification and qualification

This technology note illustrates the benefits of combining dedicated analysis software with a high-performance Raman instrument and how Renishaw supplies an effective, user-friendly solution to provide complementary information to the multitude of established HTS techniques commercially available.

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This note shows how the RA802 Pharmaceutical Analyser can be used to analyse a range of samples, such as powder blends and tablets, to screen for the presence and form of APIs

Application note: Detecting small amounts of multiple API polymorphic forms in powder blends

This note shows how the RA802 Pharmaceutical Analyser can be used to analyse a range of samples, such as powder blends and tablets, to screen for the presence and form of APIs

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The ability to group highly similar spectral data is a key result for research areas including biology and medicine. It enables qualitative conclusions to be drawn objectively based on statistics, rather than subjectively based on an analyst’s experience.

Product note: Cluster analysis and data classification

The ability to group highly similar spectral data is a key result for research areas including biology and medicine. It enables qualitative conclusions to be drawn objectively based on statistics, rather than subjectively based on an analyst’s experience.

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Plastics are extensively used in products and packaging and, unfortunately, make their way into the environment, causing significant issues for wildlife. In addition to concerns about bulk plastic contamination, there has been much interest in microplastics. Raman spectroscopy, an optical scattering technique, has much to offer researchers investigating plastics, as it can identify them rapidly and non-destructively.

Application note: Analysing microplastics with the inVia™ confocal Raman microscope

Plastics are extensively used in products and packaging and, unfortunately, make their way into the environment, causing significant issues for wildlife. In addition to concerns about bulk plastic contamination, there has been much interest in microplastics. Raman spectroscopy, an optical scattering technique, has much to offer researchers investigating plastics, as it can identify them rapidly and non-destructively.

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The Renishaw inVia confocal Raman microscope is ideal for the 2D and 3D chemical analysis of polymers. Synthetic polymers display a broad range of properties and are extensively used in modern products. The study of polymers in terms of identification, spatial distribution and concentration is important as we search for novel materials, improve effectiveness of existing materials, and reduce the costs of products. The inVia microscope provides chemical specificity and sensitivity, in a non-destructive manner, with no sample manipulation and preparation required.

Application note: Study polymers with the inVia confocal Raman microscope

The Renishaw inVia confocal Raman microscope is ideal for the 2D and 3D chemical analysis of polymers. Synthetic polymers display a broad range of properties and are extensively used in modern products. The study of polymers in terms of identification, spatial distribution and concentration is important as we search for novel materials, improve effectiveness of existing materials, and reduce the costs of products. The inVia microscope provides chemical specificity and sensitivity, in a non-destructive manner, with no sample manipulation and preparation required.

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Renishaw’s inVia confocal Raman microscope is ideally suited to the analysis of microplastics. A combination of optical and Raman imaging techniques with Renishaw's WiRE software are used to locate, image and characterise particles.

Technical note: Using the inVia Raman microscope for locating and characterising microplastics

Renishaw’s inVia confocal Raman microscope is ideally suited to the analysis of microplastics. A combination of optical and Raman imaging techniques with Renishaw's WiRE software are used to locate, image and characterise particles.

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Application note detailing how the Virsa Raman analyser can be used to analyse polymer fibres.

Application note: Analysis of polymer fibres using the Virsa™ Raman analyser

Application note detailing how the Virsa Raman analyser can be used to analyse polymer fibres.

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The Renishaw inVia confocal Raman microscope is the ideal system for the complete 2D and 3D chemical analysis of emulsions and colloids.

Application note: Study emulsions using the inVia confocal Raman microscope

The Renishaw inVia confocal Raman microscope is the ideal system for the complete 2D and 3D chemical analysis of emulsions and colloids.

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Chemically characterise your coatings with Renishaw’s inVia confocal Raman microscope. It is the ultimate system for studies ranging from fundamental research on the materials involved through to final product quality control and failure analysis.

Application note: Analyse coatings with the inVia™ confocal Raman microscope

Chemically characterise your coatings with Renishaw’s inVia confocal Raman microscope. It is the ultimate system for studies ranging from fundamental research on the materials involved through to final product quality control and failure analysis.

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Application note showing how easy it is to analyse liquids with the Virsa Raman analyser

Application note: Analysing liquids with the Virsa™ Raman analyser

Application note showing how easy it is to analyse liquids with the Virsa Raman analyser

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Monitoring the crystallographic phase changes of potassium nitrate using the inVia Raman microscope

Application note: Monitoring phase changes

Monitoring the crystallographic phase changes of potassium nitrate using the inVia Raman microscope

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Application note detailing how the Virsa Raman analyser can be used to study catalysts, with vanadium oxide as an example.

Application note: Analysing catalytic powders with the Virsa™ Raman analyser

Application note detailing how the Virsa Raman analyser can be used to study catalysts, with vanadium oxide as an example.

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